The Impact of Social Media on Life Satisfaction: The Mediating Role of Social Comparison, Envy and Self- Esteem

In this paper we discuss the associations between social media use, life satisfaction, social comparison, life envy, and self-esteem. The sample included 390 Egyptian subjects aged (18-35) (M=20.94, SD=2.08). The results of analysis conducted using partial correlation and linear regression revealed that the use of social media negatively affects the levels of life satisfaction (p=0.39, R2=0.15). Findings are also discussed within the contexts of the mediating role of social comparison, envy, and self-esteem in connection with social media use and life satisfaction

Study Of The Behaviour Of Wind Turbines Using Doubly Feed Asynchronous Generator During Voltage Dip

The work presented in this communication, describes a solution for wind turbines using Double Fed Induction Generator (DFIG) to overcome the disruption caused by Voltage dips. The solution is to avoid that the strong rotor intensity damage the converter and the generator to disconnect from the network. It will focus on the CROWBAR system to show his contribution and limitations face the grid defaults. Simulations show that the CROWBAR associated with variable resistance gives good results

Multiple Regression Prediction Model for Cutting Forces in Turning Carbon-Reinforced PEEK CF30

Among the thermoplastic polymers available, the reinforced polyetheretherketone with 30% of carbon fibres (PEEK CF 30) demonstrates a particularly good combination of strength, rigidity, and hardness, which prove ideal for industrial applications. Considering these properties and potential areas of application, it is necessary to investigate the machining of PEEK CF30. In this study, response surface methodology was applied to predict the cutting forces in turning operations using TiN-coated cutting tools under dry conditions where the machining parameters are cutting speed ranges, feed rate, and depth of cut. For this study, the experiments have been conducted using full factorial design in the design of experiments (DOEs) on CNC turning machine. Based on statistical analysis, multiple quadratic regression model for cutting forces was derived with satisfactory 2-squared correlation. This model proved to be highly preferment for predicting cutting forces

MPHT-Promoted Bromocyclization of ortho-Substituted Arylalkynes: Application to the Synthesis of 2-Substituted 3-Bromobenzofurans and -Benzo[b]thiophenes

International audienceA convenient and general approach to the synthesis of 2‐substituted 3‐bromobenzofurans and ‐benzothiophenes was developed. The procedure is based on the cyclization of ortho‐substituted arylalkynes in the presence of N‐methylpyrrolidin‐2‐one hydrotribromide (MPHT) as a soft and easy‐to‐handle electrophilic brominating reagent. Under mild reaction conditions, MPHT promoted the bromocyclization of various enynes and diynes as well as arylalkynes to give 2‐substituted 3‐bromobenzofurans and ‐benzothiophenes in high to excellent yields. Subsequent functionalization by palladium‐catalyzed coupling reactions at the C–Br bond afforded general access to 2,3‐disubstituted benzofurans and benzothiophenes of biological interest

Bortezomib in Kidney Transplantation

Although current therapies for pretransplant desensitization and treatment of antibody-mediated rejection (AMR) have had some success, they do not specifically deplete plasma cells that produce antihuman leukocyte antigen (HLA) antibodies. Bortezomib, a proteasome inhibitor approved for the treatment of multiple myeloma (a plasma cell neoplasm), induces plasma cell apoptosis. In this paper we review the current body of literature regarding the use of this biological agent in the field of transplantation. Although limited experience with bortezomib may seem to show promise in the realm of transplant recipients desensitization and treatment of AMR, there is also experience that may suggest otherwise. Bortezomib's role in desensitization protocols and treatment of AMR will be defined better as more clinical data and trials become available

A new framework for electricity price forecasting via multi-head self-attention and CNN-based techniques in the competitive electricity market

Due to recent technical improvements, the smart grid has become a feasible platform for electricity market participants to successfully regulate their bidding process based on demand-side management (DSM) perspectives. At this level, practical design, implementation, and assessment of numerous demand response mechanisms and robust short-term price forecasting development in day-ahead transactions are all critical. The accuracy and effectiveness of the day-ahead price forecasting process are crucial concerns in a deregulated market. In this market, the reason for low accuracy is the limitation of electricity generation compared to the electricity demand variations. Hence, this study proposes a suitable technique for forecasting electricity prices using a multi-head self-attention and Convolutional Neural networks (CNN) based approach. Further, this study develops a feature selection technique using mutual information (MI) and neural networks (NN) to choose suitable input variable subsets significantly affecting electricity price predictions simultaneously. The combination of MI and NN reduces the number of input features used in the model, thereby decreasing the computational complexity of the NN. The actual data sets from the Ontario electricity market in 2020 are acquired to verify the simulation results. Finally, the simulation results proved the efficiency of the proposed method by demonstrating increased accuracy by attaining the lowest average value for MAPE and RMSE with a value of 1.75% and 0.0085, respectively, and compared to results obtained by recent computational intelligence approaches. By attaining accurate electricity price results, the significance of this study can be summed up as aiding the electricity industry's operators in administering effective energy management, efficient resource allocation, and informed decision-making.© 2023 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).fi=vertaisarvioitu|en=peerReviewed

Résolution des équations d'érosion interne dans les sols par développement asymptotique

On considère dans ce travail le phénomène d'érosion interne se produisant dans un milieu monodimensionnel. Les équations couplées de ce problème qui comprennent la consolidation, l'érosion et le transport des particules érodées sont résolues par une méthode numérique utilisant un développement asymptotique. La variable échelle choisie étant définie par la variation maximale de porosité. Une étude paramétrique en fonction de la pérméabilité, de la résistance à l'érosion et du gradient hydraulique a été ensuite effectuée

Implementation of an Affordable Method for MPS Diagnosis from Urine Screening to Enzymatic Confirmation: Results of a Pilot Study in Morocco

Background: Rapid and accurate diagnosis of mucopolysaccharidoses (MPS) is still a challenge due to poor access to screening and diagnostic methods and to their extensive clinical heterogeneity. The aim of this work is to perform laboratory biochemical testing for confirming the diagnosis of mucopolysaccharidosis (MPS) for the first time in Morocco. Methods: Over a period of twelve months, 88 patients suspected of having Mucopolysaccharidosis (MPS) were referred to our laboratory. Quantitative and qualitative urine glycosaminoglycan (GAG) analyses were performed, and enzyme activity was assayed on dried blood spots (DBS) using fluorogenic substrates. Enzyme activity was measured as normal, low, or undetectable. Results: Of the 88 patients studied, 26 were confirmed to have MPS; 19 MPS I (Hurler syndrome; OMIM #607014/Hurler-Scheie syndrome; OMIM #607015), 2 MPS II (Hunter syndrome; OMIM #309900), 2 MPS IIIA (Sanfilippo syndrome; OMIM #252900), 1 MPS IIIB (Sanfilippo syndrome; OMIM #252920) and 2 MPS VI (Maroteaux-Lamy syndrome; OMIM #253200). Parental consanguinity was present in 80.76% of cases. Qualitative urinary glycosaminoglycan (uGAGs) assays showed abnormal profiles in 31 cases, and further quantitative urinary GAG evaluation and Thin Layer Chromatography (TLC) provided important additional information about the likely MPS diagnosis. The final diagnosis was confirmed by specific enzyme activity analysis in the DBS samples. Conclusions: The present study shows that the adoption of combined urinary substrate analysis and enzyme assays using dried blood spots can facilitate such diagnosis, offer an important tool for an appropriate supporting care, and a specific therapy, when available

Effect of Tadalafil on Penile Duplex parameters in Erectile Dysfunction Patients

Background: Tadalafil is a PDE-5 (phosphodiesterase inhibitor) inhibitor that supports endogenous nitric oxide's vasodilatory actions and aids in erection maintenance. The penile duplex has proven to be very useful for imaging superficial structures and for determining the reasons of erectile dysfunction (ED). Objectives: To assess the effect of daily oral tadalafil 5mg for 3 months on penile duplex parameters in erectile dysfunction patients. Patients and Methods: A case control study involved 30 Egyptian patients ED. Appropriate clinical history and penile duplex examination before and after treatment with daily oral tadalafil mg for 3 months were performed. Results: The mean age of the patients was 53.17 ± 7.8 years. We founded that there was significant (p < 0.001) improvement in the level of erection after treatment. The rate of erection E1 and E2 was decreased from 53.3% to 3.3%. Likewise, the rate of E3-E5 was increased from 46.7% to 96.7%. Moreover, the mean duration of erection was elongated from 24.7 ± 5.3 to become 37.4 ± 3.8 and this was statistically significant (p < 0.001). Also, the mean peak systolic volume (PSV) was significantly (p = 0.001) increased after treatment (38.4 ± 9.1 cm/s) compared with the pre-treatment levels (23.9 ± 6.1 cm/s). Unlikely, the mean end diastolic volume (EDV) was insignificantly (p = 0.340) lower in post-treatment (2.25 ± 0.5 mL) compared with pre-treatment levels (2.97 ± 0.4 mL). Likely, the mean resistant index (RI) showed insignificant difference (p = 0.965) after treatment (0.9 ± 0.02) compared with before treatment (0.9 ± 0.08). For penile artery diameter, there was significant (p = 0.009) increase in the diameter after treatment (0.9 ± 0.1 mm) compared with before treatment (0.8 ± 0.1 mm). Conclusion: Oral daily tadalafil 5mg for 3 months is considered an effective treatment for ED according to penile duplex parameters